منابع مشابه
Maraviroc (Celsentri) for multidrug-resistant human immunodeficiency virus (HIV)-1.
(1) Maraviroc belongs to a new class of antiretroviral drugs designed to block entry of HIV-1 into CD4+ T-cells via the CCR5 coreceptor. It is indicated for combination therapy in treatment-experienced adults infected with CCR5-tropic HIV-1 that is resistant to multiple antiretroviral agents. (2) Results from two randomized controlled trials (RCTs) indicate that in treatment experienced patient...
متن کاملViral escape in the CNS with multidrug-resistant HIV-1
INTRODUCTION HIV-1 viral escape in the cerebrospinal fluid (CSF) despite viral suppression in plasma is rare [1,2]. We describe the case of a 50-year-old HIV-1 infected patient who was diagnosed with HIV-1 in 1995. Antiretroviral therapy (ART) was started in 1998 with a CD4 T cell count of 71 cells/ìL and HIV-viremia of 46,000 copies/mL. ART with zidovudine (AZT), lamivudine (3TC) and efavirenz...
متن کاملHIV and multidrug-resistant tuberculosis: overlapping epidemics.
People infected with Mycobacterium tuberculosis and HIV are much more likely to develop active tuberculosis (TB) than people with M. tuberculosis but without HIV [1]. Patients infected with multidrugresistant (MDR)-TB (defined as resistance to at least rifampicin and isoniazid, the two most powerful antiTB drugs) require longer, more expensive treatment regimens than drug-susceptible TB, with p...
متن کاملHIV and multidrug-resistant tuberculosis: overlapping epidemics
People infected with Mycobacterium tuberculosis and HIV are much more likely to develop active tuberculosis (TB) than people with M. tuberculosis but without HIV [1]. Patients infected with multidrugresistant (MDR)-TB (defined as resistance to at least rifampicin and isoniazid, the two most powerful antiTB drugs) require longer, more expensive treatment regimens than drug-susceptible TB, with p...
متن کاملStudy of HIV seroprevalence in Pulmonary Tuberculosis Patients with Special Reference to Multidrug Resistant Mycobacteria
This study was planned to determine HIV seroprevalence among pulmonary tuberculosis patients, to characterize the isolated mycobacteria into typical and atypical strains and to evaluate the drug resistant pattern of mycobacterial isolates. The study aims to correlate multidrug resistance (MDR) and HIV seropositivity status in pulmonary tuberculosis patients. During the year 1994-1997, 750 pulmo...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2004
ISSN: 1058-4838,1537-6591
DOI: 10.1086/383581